Screen/film mammography - X-ray tube
Xray energy level required for optimal contrast in the breast is 20 keV
Higher energy = decreased contrast
Lower energy = inadequate penetration of the breast and increased radiation dose
Molybdenum and Rhodium are used as target materials in the anode
Both produce xray radiation at the optimal energy level
Mo = 17.9-19.5 keV
Rh = 20.2-22.7 keV
Provides better penetration in thick/dense breasts
Xrays are slightly higher energy
To produce these characteristic xrays, the xray tube peak voltage must be higher than these values (25-30 kVp)
Typical xray tube current is 80-100 mA
Exposure time is about 1 sec
Can be longer for dense thick breasts (<=4 sec)
Xray tube filters
Xray tube window - Beryllium - minimizes xray beam attenuation
Mo filters are used to remove bremsstrahlung radiation (high energy)
30 nanometers thick
Improves contrast
Filters out very low energy xrays -> decrease patient dose
Use Ro filter for a Ro anode
Target-filter recommendations
Fatty breast up to 4 cm thick
Mo target and 30 micron Mo filter
24-26 kVp
Glandular breast 5-7 cm
Mo target and 25 micron Rh filter
27-31 kVp
Breast thickness >7 cm
Rh target and 25 micron Rh filter
FILTERS: DBT
Filters:
RH = for 2D only
Silver/Ag (25.5 keV) = for 2D only (thick/dense breasts)
Aluminum/Al (1.8 keV) = for 3D tomo only
Anode is Tungsten (58.0-67.2 keV)
No grid
<3 mGy for both 2D and DBT acquisition
Synthetic view (C-view) - reconstruction of a mammogram from a stack of tomo images
3D tomo: 1.45 mGy
Combo: 2.65 mGy
Grids
Grids are used to maximize image quality by (1) reducing scatter and (2) improving contrast
Scatter increases w/ breast thickness and peak voltage
Mammography usually uses moving grids
Typical ratios are 4:1 or 5:1
Downside of grids = increase patient dose 3x
Radiation dose
Radiation is a carcinogen
No known cases of mammography induced breast CA
Mantle radiation for Hodgkin's lymphoma has been associated w/ radiation induced breast CA
Breast dose
Mean glandular dose (MGD) - measure of dose in mammography
Can be estimated from the measured entrance skin exposure, xray beam peak voltage and the half-value layer
Dependent on breast composition - assumes 50% glandular tissue and 50% adipose tissue
Use of grid doubles MGD
ACR recommends that the MGD for a 4.2 cm thickn breast be <3 mGy for screen/film w/ grid and digital full field w/ grid.
Most radiation induced breast CA result from MGD of 1-20 Gy.
Risk of radiation induced breasts CA is 1 in 10,000.
Risk of a fatal breast CA is 1 in 200-250
Use 12 for deep things
Use 17 for most things bc it shows superficial structures