Unilateral Axillary LN DDX
Breast carcinoma w axillary spread, reactive LAD, mets/lymphoma, systemic dz, granulomatous dz
Bilateral Axillary LN DDX
CLL, HIV, granulomatous dz (sarcoid, TB), collagen vascular dz (RA, SLE), metastatic dz (breast/nonbreast CA), reactive
Work up
Lymphadenopathy on mammo -> US -> bx -> hematologic wu
Unilateral axillary adenopathy
CA till proven otherwise.
Bilateral axillary adenopathy
More likely due to systemic diseases; CLL is MCC of bilateral axillary LAD seen on screening. autoimmune / collagen vasculare disease/ acute HIV, COVID vaccination.
Morphologically normal with calcs
Calcs without normal LN morphology